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Here's what you should always look for in my opinion, I usually also do bloodwork every 3 months to make sure everything is good to go before a blast or returning on a cruise dose : Testosterone Total / Free testosterone SHBG E2 Prolactin Lipid panel Hematocrit Hemoglobin Creatinine ALT / AST (Liver) Blood Urea Nitrogen (Kidney) PSA (Prostate - Elevated values seen after a blast but goes back to normal during cruise normally) If lipid panel is elevated LDL and really low HDL, normally you want to fix your diet before going back on a blast. Always get E2 checked out if you feel down, no libido, getting gyno etc. Althought E2 is great for putting on some mass (pretty clear by now that studies are showing E2 is a great muscle builder) you don't want it too high because of those issues and also dont want to crash it with an AI. Get it checked out, then see if you need an AI or not. For SHBG, this one is tricky, I feel better honestly when T frees up and when its not bound to SHBG, normally I would take either masteron or proviron to get it down. Prolactin to check when taking any 19-Nors