by the sounds of things, your best bet would be to completely come off of everything in my opinion do a complete reset, get everything back to where it should be pick up some liv52, probiotics, digestive enzymes, and for the joint pain pick up some sort of joint care, i know truenutrition has one and canadianprotein, ive used both and noticed improvements, you can also throw in 2iu of hgh, or cjc with dac or mk677, which was recommended to me by a phew people, cause ive been going through the same thing with appetite issues. i was running t400, tren hex, tbol and injectable winny, decided to drop the tbol to see if that would help my case which it didnt, and as of this past monday ive dropped everything, doing a complete reset, and going for bloodwork either this week or next.