Jetpilot Posted November 19, 2018 Share Posted November 19, 2018 (edited) Hi Guys Because it is hard to get it in Canada this is my source for Tudca they shipped from USA pretty fast( 6-7 days) no problem with custom I like that it include NAC as well one pills do all I use it year around but I am sure it will be enough to use it on cycle only and if you use oral just double the dose daly , Tudca is the best supplement for liver protection by far! ps: I am not related to this guy this is a true review! https://www.amazon.ca/Clear-TUDCA-Tauroursodeoxycholic-N-acetyl-Cysteine/dp/B00GPONVD8/ref=sr_1_4?ie=UTF8&qid=1542647468&sr=8-4&keywords=Gun+Show+Supplements Edited November 19, 2018 by Jetpilot mistake 2 Quote Link to comment Share on other sites More sharing options...
Local Dipshit Posted November 19, 2018 Share Posted November 19, 2018 Yep this is the one I use and where I get it from always. This stuff works Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 19, 2018 Author Share Posted November 19, 2018 Since I did a Cycle with bad Anavar and my liver enzyme shoot over 900+ I don’t take chance anymore ! I will post my blood test to prove my point Quote Link to comment Share on other sites More sharing options...
Local Dipshit Posted November 19, 2018 Share Posted November 19, 2018 2 minutes ago, Jetpilot said: Since I did a Cycle with bad Anavar and my liver enzyme shoot over 900+ I don’t take chance anymore ! I will post my blood test to prove my point I hear ya bro sounds good Quote Link to comment Share on other sites More sharing options...
Blitz Posted November 20, 2018 Share Posted November 20, 2018 Anyone have any insight into the raw cost of this? Is it just a low demand leading to low supply and high price? You really should be using 1g of it and to dose it there it's very expensive. 1 Quote Link to comment Share on other sites More sharing options...
Local Dipshit Posted November 20, 2018 Share Posted November 20, 2018 56 minutes ago, Blitz said: Anyone have any insight into the raw cost of this? Is it just a low demand leading to low supply and high price? You really should be using 1g of it and to dose it there it's very expensive. Good question as I’d like to know too, be cool if a sponsor could carry this in raw at some point! Quote Link to comment Share on other sites More sharing options...
BendingBars Posted November 21, 2018 Share Posted November 21, 2018 Ive seen it for $2.24 USD/g Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 21, 2018 Author Share Posted November 21, 2018 Cheap man always pay twice lol Quote Link to comment Share on other sites More sharing options...
Nissan Posted November 21, 2018 Share Posted November 21, 2018 I use Liv.52 instead. Pretty solid stuff! Multiple studies have been done on it. Easily available & half the price! 1 Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 21, 2018 Author Share Posted November 21, 2018 1 hour ago, Nissan said: I use Liv.52 instead. Pretty solid stuff! Multiple studies have been done on it. Easily available & half the price! Nissan this time I know what I am talking about , I have a liver disease call liver Primary Sclerosing cholangitis this is a incurable disease , that said Tudca is the supplement version of Ursodeoxycholic acid (UDCA) who is a very strong liver medication , I ask question to the number one doctor for liver transplant in Toronto General about it for him Liv.52 or anything else is helping yes but not protecting on harsh oral’s. - My experience I try many times to use oral’s with disaster result on liv52 milk thistle my liver enzyme always shoot up by 500+ so I stop using oral’s when that doctor told me that Tudca was almost the same thing as the medication I take in supplement form I give a shot at my surprise my enzyme have stay normal since , I am on a Anadrol cycle after the 6 week I will post the blood result. Can you post your multiple result of men or woman using liv.52 on AAS please? 1 Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 21, 2018 Author Share Posted November 21, 2018 here we go ! 5) Tauroursodeoxycholic acid (TUDCA) - this is a relatively recent new liver aid , introduced in the market as a supplement by thermolife(LIVER LONGER) it looks like a very good help in preventing cholestasis, one of the major risk with 17 alkylated steroids: TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCα?ezrin pathway Cholestasis, induced by liver ischemia-reperfusion injury (IRI), is characterized by dilatation of bile canaliculi and loss of microvilli. Tauroursodeoxycholic acid (TUDCA) is an anti-cholestatic agent, modulating protein kinase C (PKC) α pathway. PKC reduces ischemic damage in several organs, its isoform α modulates ezrin, a key protein in the maintenance of cell lamellipoidal extensions. We evaluated the effects of TUDCA on cholestasis, canalicular changes and PKCα?ezrin expression in a rat model of liver IRI. Livers flushed and stored with Belzer solution or Belzer + 10 mm TUDCA (4 ?C for 6 h) were reperfused (37 ?C with O2) with Krebs?Ringer bicarbonate + 2.5 μmol/min of Taurocholate or TUDCA. Bile was harvested for bile flow assessment. Liver tissue was employed for Electron Microscopy (EM) and for PKCα and ezrin immunoblot and immunofluorescence. The same experiments were conducted with the PKCα inhibitor Go-6976. TUDCA-treated livers showed increased bile flow (0.25 ? 0.17 vs. 0.042 ? 0.02 μl/min/g liver, P < 0.05) and better preservation of microvilli and bile canalicular area at EM. These effects were associated with increased PKCα and ezrin expression (P = 0.03 and P = 0.04 vs. control respectively), as also confirmed by immunofluorescence data. PKCα inhibition abolished these TUDCA effects. TUDCA administration during IRI reduces cholestasis and canalicular damage in the liver modulating PKCα?ezrin pathway. 1 Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 21, 2018 Author Share Posted November 21, 2018 report from Mayo clinic. Abstract The short-term ability of tauroursodeoxycholic acid (TUDCA) to lower the blood levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transpeptidase (GGT) in patients with hypertransaminasemia and chronic active hepatitis was assessed in a 3-month, randomized, controlled clinical trial. A total of 53 patients with histologic evidence of chronic active hepatitis in a liver biopsy sample and an increase in the serum values of ALT of at least twice the upper limit of normal in two separate checkups in the previous 6 months were enrolled in the study. TUDCA 500 mg/day divided into two doses with meals was given to 27 patients; the remaining 26 patients served as controls. Follow-ups were performed in both the treated and control patients at 1 month, 2 months, and the end of the study period. All patients completed the study. The effect of TUDCA on liver serum enzymes was evident after 1 month and reached a maximum effect after 3 months, when TUDCA had significantly lowered AST (−44%), ALT (−49%), and GGT (−38%) (P < 0.001, compared with baseline values). Throughout the study, serum levels of alkaline phosphatase and bilirubin remained within a normal range in all patients. A spontaneous slight decrease in AST (11% to 14%), ALT (13% to 15%), and GGT (5% to 7%) was observed in the control group during the study. None of the patients receiving TUDCA reported side effects. Dyspeptic symptoms were evident in 70% of the TUDCA patients and 62% of the controls and were individually scored at the beginning of the trial. After 3 months, the score decreased significantly in the TUDCA group but not in the control group (P < 0.001). Short-term therapy with TUDCA is effective in lowering serum levels of transaminases and GGT, is free of hepatotoxic effects, and improves dyspeptic symptoms in patients with chronic active hepatitis. Further studies are needed to investigate the influence of TUDCA therapy on the natural history of chronic active hepatitis. Quote Link to comment Share on other sites More sharing options...
Nissan Posted November 21, 2018 Share Posted November 21, 2018 5 minutes ago, Jetpilot said: Nissan this time I know what I am talking about , I have a liver disease call liver Primary Sclerosing cholangitis this is a incurable disease , that said Tudca is the supplement version of Ursodeoxycholic acid (UDCA) who is a very strong liver medication , I ask question to the number one doctor for liver transplant in Toronto General about it for him Liv.52 or anything else is helping yes but not protecting on harsh oral’s. - My experience I try many times to use oral’s with disaster result on liv52 milk thistle my liver enzyme always shoot up by 500+ so I stop using oral’s when that doctor told me that Tudca was almost the same thing as the medication I take in supplement form I give a shot at my surprise my enzyme have stay normal since , I am on a Anadrol cycle after the 6 week I will post the blood result. Can you post your multiple result of men or woman using liv.52 on AAS please? I did not know about your medical condition. Sorry to hear that. I have been using Liv52 for a long time now, and it has definitely helped me along the way. My liver is not the strongest, I had a severe case of Hepatitis (jaundice) when I was younger. I just posted a thread about Liv 52 and link to some of the studies. Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted November 21, 2018 Author Share Posted November 21, 2018 Just now, Nissan said: I did not know about your medical condition. Sorry to hear that. I have been using Liv52 for a long time now, and it has definitely helped me along the way. My liver is not the strongest, I had a severe case of Hepatitis (jaundice) when I was younger. I just posted a thread about Liv 52 and link to some of the studies. Thank you brother! I think with the difference and prices better be safe then sorry I promise you something I know very well now that the liver is one of the most important organ we have 1 Quote Link to comment Share on other sites More sharing options...
Local Dipshit Posted November 21, 2018 Share Posted November 21, 2018 Good info @Jetpilot Quote Link to comment Share on other sites More sharing options...
Blitz Posted January 22, 2019 Share Posted January 22, 2019 Just ordered some.. Been feeling off after running dbol for 7 weeks at 25mg. Adding this in 500mg at dinner see what happens. Quote Link to comment Share on other sites More sharing options...
funlog Posted February 17, 2019 Share Posted February 17, 2019 In regards to the original link, just curious, how many are you taking a day, one or two? Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted February 17, 2019 Author Share Posted February 17, 2019 1 minute ago, funlog said: In regards to the original link, just curious, how many are you taking a day, one or two? I Take 2x on cycle that include orals one morning one night and one year around I am on TRT! everything stay in the green band like this! Quote Link to comment Share on other sites More sharing options...
Cheapshot Posted February 17, 2019 Share Posted February 17, 2019 15 minutes ago, Jetpilot said: I Take 2x on cycle that include orals one morning one night and one year around I am on TRT! everything stay in the green band like this! You take tudca year round? Seems like a waste Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted February 17, 2019 Author Share Posted February 17, 2019 Just now, Cheapshot said: You take tudca year round? Seems like a waste I have a history with my liver at one point it did spike like crazy, because of my job I can’t have this anymore better be safe then sorry! Quote Link to comment Share on other sites More sharing options...
funlog Posted February 17, 2019 Share Posted February 17, 2019 29 minutes ago, Jetpilot said: I Take 2x on cycle that include orals one morning one night and one year around I am on TRT! everything stay in the green band like this! Thanks Jetpilot, appreciate the help. Quote Link to comment Share on other sites More sharing options...
Blitz Posted February 17, 2019 Share Posted February 17, 2019 12 hours ago, funlog said: In regards to the original link, just curious, how many are you taking a day, one or two? I've been taking two pills. Seems like that is the lowest effective dose in studies and also you don't need to run it too long for the benefits. One bottle as you're finishing orals. Quote Link to comment Share on other sites More sharing options...
funlog Posted March 1, 2019 Share Posted March 1, 2019 Wow this stuff stinks, lol. Quote Link to comment Share on other sites More sharing options...
Blitz Posted March 1, 2019 Share Posted March 1, 2019 7 hours ago, funlog said: Wow this stuff stinks, lol. And burns the tongue just from the residue on the caps Quote Link to comment Share on other sites More sharing options...
Jetpilot Posted March 1, 2019 Author Share Posted March 1, 2019 Yesterday I did have my 6 month check with my liver specialist and everything is in the green ! officially discharged and next check in 2 years ! Tudca work ! 2 Quote Link to comment Share on other sites More sharing options...
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