sjgpharma Posted November 29, 2018 Share Posted November 29, 2018 What Is GW0742? GW0742 is a selective PPARδ agonist (EC50 = 1.1 nM) that exhibits 1,000-fold selectivity over the other human PPAR subtypes. GW0742 exhibits time-dependent neuroprotection in low KCl-induced apoptosis in cerebellar granule neuronal cultures. Despite the neuroprotective properties observed, prolonged (48h) incubation with GW0742 produced significant inherent toxicity. This cell death was determined to be apoptotic as identified with the TUNEL assay. Solubility Chloroform (Slightly), Methanol (Slightly) Quote Link to comment Share on other sites More sharing options...
Rosconow Posted November 29, 2018 Share Posted November 29, 2018 Never heard of it.... Good thing too, seems to promote cell death? Quote Link to comment Share on other sites More sharing options...
sjgpharma Posted November 30, 2018 Author Share Posted November 30, 2018 Here you have it lol. It is used for the treatment of obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR , as the combination has been shown to significantly increase exercise endurance in human. Have you heard of S23, LGD-3033, SR9011, ACP-105 and AC-262536? There are some SARMs even unknown by the vet. Quote Link to comment Share on other sites More sharing options...
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