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HMG/HCG results someone explain this


a_ahmed
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https://journals.lww.com/md-journal/fulltext/2019/08020/optimal_treatment_for_spermatogenesis_in_male.25.aspx

Can someone smart look at this and explain to me the action and results?

I am thinking of how to produce sperm... I am on HRT and have 0 sperm... and off HRT crap low 80 year old test, despite clomid/etc... so I always knew HMG which is pricey can help but its like daily injections. This study talks about weekly injections of HCG and HMG. I don't know someone give me some hope.

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On HRT there have been studies done that have shown combinations of clomid, HCG and to a lesser extent hmg will bring sperm into the normal range 20mill +

If you're hrt is real hrt (100-200mg a week/every other week) running 50mg of clomid a day and 1000iu of HCG every 3 days for at least 8 weeks or until you get her pregnant will probably do the trick.

I was at the end of a cycle where I used deca and tren, my levels were nearly 0. While still on test and tren I did HCG every 3 days after my initial sperm test. I did 5000 for my first two shots, 2500 for my 3rd and 4th and 1000 thereafter. After 6 weeks my count was 9 million. I've now come off completely and running clomid. I'll be testing in another month or so hopefully I'm back up at 20,000,000+. Really if you're within a few years of having kids you should run 500iu of HCG e3d when you're on from the first week till the last.

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We just did IVF for the third time... and it's a failure. I've had hypogonadism and fertility issues since my early 20s, never touched gear up to until after I was on HRT..

Before HRT or any treatments i naturally had lower test at one point but more importantly had 1 million sperm this was when i was 23...

I tried HCG,etc.. and no change got hrt and felt better but it made my sperm count 0. I got off and was on clomid for 4 months and could only produce 2mill max... and then 1 mill, half mill etc... so i froze a bunch of samples... i tried ivf 2x with my ex...

Now 3x with my current wife... and we just got the bad news today... no eggs went to blastocyst...

My wife just and I just cried for over an hour...

I am trying to see what drug combinations i could try either way it may require ivf and we have no money no more...

I have one more sample frozen... and then im completely out and now i am 36 and aging...

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I dont know what hmg protocol would be if maybe it could help thats why i was wondering...

and if we do ivf if now that BT has it.. we could at least get it a bit cheaper than in pharmacy........ she was on a high dose.... we spent 20 grand.... we are now broke...

Edited by a_ahmed
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1 hour ago, a_ahmed said:

I dont know what hmg protocol would be if maybe it could help thats why i was wondering...

and if we do ivf if now that BT has it.. we could at least get it a bit cheaper than in pharmacy........ she was on a high dose.... we spent 20 grand.... we are now broke...

If you're getting IVF I'm sure the fertility specialists would have brought up hmg if they thought it would work for you. I would talk to the doc regardless see if they think hmg+HCG+clomid could still help. If you have workplace insurance it will all be covered most likely.

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No we don't have insurance coverage on it...

We went with first two attempts with government funded IVF and paid medications ourselves.

The first attempt doctors screwed up (made us not come in for bloodwork and she was supposed to take meds but didnt because of them) So they cancelled it but it counted as an attempt.

Second attempt got pregnant but we lost the child almost 3 months in...

And now fully paid everything ourselves 20k... and no embryos could be frozen... at day 3 was good but at day 5 2 remained and day 6 all arrested. They wanted blastocyst only... we insisted day 3... due to covid had to freeze..

I have only one sample left...

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17 hours ago, a_ahmed said:

No we don't have insurance coverage on it...

We went with first two attempts with government funded IVF and paid medications ourselves.

The first attempt doctors screwed up (made us not come in for bloodwork and she was supposed to take meds but didnt because of them) So they cancelled it but it counted as an attempt.

Second attempt got pregnant but we lost the child almost 3 months in...

And now fully paid everything ourselves 20k... and no embryos could be frozen... at day 3 was good but at day 5 2 remained and day 6 all arrested. They wanted blastocyst only... we insisted day 3... due to covid had to freeze..

I have only one sample left...

I'm not sure man. I don't know what BT price is but regular treatment of hmg for fertility is 75-150iu everyday for months. Minimum 2 months before you start to get a real effect. I know at the pharmacy 75iu is like $10. Getting a prescription usually is cheaper than underground. If there is a real medical need it's always better to look to a doc.

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7 hours ago, a_ahmed said:

We were paying way more for menopur... it was almost like 1000 bux a day if i recall ill have to check the bill details...
 

menopur is 75iu fsh and 75iu lh in one vial

Are you in Canada? My wife may have to take daily FSH and the entire pen which would dose for a month is $100

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wtf... we went to the pharmacy and got the prescription from the fertility docs... Both menopur (which she used this time) and gonal f (which was the pen and we used last time alongside menopur if i recall) cost so much...... definetely not 100 for a whole month.. this was for IVF/ICSI, not IUI, i dont think they even use this for IUI... for IUI i think they give clomid

 

For all meds it cost us around $8000~

Deccapeptyl x2

Orgalutron (i think it was 8 total)

Ovidrel (I think 1 only?)

I think triptorelin also? I forget...

Majority was 75iu vials of menopur (a shit ton, as she had to take 225iu AM, 225iu PM) for a good 12 days

 

If we were to do implantation also would have had to do extra medications (progesterone for 10 weeks+), but it was meant to be done later, and only frozen due to covid now. That would have been $500-1000~ on top

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