Jump to content

Ezetimibe - Low Hanging LDL Reducing Fruit?

Recommended Posts

Ezetimibe is a type of medicine used to lower cholesterol.  Some users have reported a 50% reduction in LDL on and off cycle with 10mg day. 

It's used to treat high blood cholesterol. This is when you have too much of a fatty substance called cholesterol in your blood.

You may also be prescribed ezetimibe if you cannot take cholesterol-lowering medicines called statins, or if statins do not work for you.

Ezetimibe is available on prescription only. It comes as tablets.

Ezetimibe also comes mixed with simvastatin, a type of statin. This is known by the brand name Inegy.

Key facts:

  • Ezetimibe helps stop your body taking in cholesterol from food.
  • It usually lowers cholesterol levels within 2 weeks.
  • You can take this medicine with or without food.
  • Common side effects include stomach (abdominal) pain and diarrhoea.
  • Ezetimibe is also known by the brand name Ezetrol. It can also be mixed with simvastatin, a type of statin. This is known by the brand name Inegy.

Who can and cannot take ezetimibe:
Ezetimibe can be taken by adults and children from the age of 10 years.

Ezetimibe is not suitable for some people. To make sure it is safe for you, tell your doctor if you:

  • have had an allergic reaction to ezetimibe or any other medicines in the past
  • have liver problems
  • are pregnant, planning to become pregnant or are breastfeeding

How and when to take it:
You can take ezetimibe with or without food.

The dose for adults and children is one 10mg tablet, taken once a day.

What if I forget to take it?
If you forget to take ezetimibe, take it as soon as you remember. If you do not remember until the following day, skip the missed dose and take your next one at the usual time.

Do not take a double dose to make up for a forgotten dose. If you often forget doses, it may help to set an alarm to remind you.

You could also ask a pharmacist for advice on other ways to help you remember to take your medicine.

What if I take too much?
Taking 1 or 2 extra tablets is unlikely to harm you. But the amount of ezetimibe that can lead to overdose is different from person to person.

Side effects:
Like all medicines, ezetimibe can cause side effects in some people, although not everyone gets them.

Common side effects:
These common side effects may happen in more than 1 in 100 people.

Keep taking the medicine, but talk to a doctor if these side effects bother you or do not go away:

  • stomach (abdominal) pain
  • diarrhoea
  • farting more than usual
  • feeling more tired than usual

Serious side effects:
Serious side effects are not common and happen in less than 1 in 10,000 people.

Tell a doctor straight away if you get:

  • muscle pain, tenderness, weakness or cramps
  • yellow skin or the whites of your eyes turn yellow, pale poo and dark pee – this can be a sign of liver problems
  • severe stomach pain (just under your ribs) – this can be a symptom of pancreas problems

Serious allergic reaction:
In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to ezetimibe.

Immediate action required:

  • you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
  • you're wheezing
  • you get tightness in the chest or throat
  • you have trouble breathing or talking
  • your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

These are not all the side effects of ezetimibe. For a full list, see the leaflet inside your medicine packet.

How to cope with side effects:

  • stomach (abdominal) pain – try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help. If you're in a lot of pain, speak to a pharmacist or doctor.
  • diarrhoea – drink lots of fluids, such as water or squash, to avoid dehydration. Speak to a pharmacist if you have signs of dehydration such as peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor. Speak to a doctor if diarrhoea lasts for more than a week after you start ezetimibe.
  • farting – try to not eat foods that cause wind (such as lentils, peas, beans and onions). Eat smaller meals, eat and drink slowly, and exercise regularly. There are pharmacy medicines that may also help, such as charcoal tablets or simeticone. Peppermint tea may also help.
  • feeling tired – try to relax when possible and avoid intense exercise to see if that helps. If these symptoms do not go away after 1 to 2 weeks, ask a pharmacist or doctor for advice.

Pregnancy and breastfeeding:
Ezetimibe is not usually recommended during pregnancy or while breastfeeding. This is because there is very little information about its safety.

A doctor may suggest another medicine for lowering cholesterol, such as colestyramine.

Speak to a doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

Cautions with other medicines:
Some medicines can affect the way ezetimibe tablets work. They may also make your more likely to get side effects.

Tell a doctor if you're taking these medicines before you start ezetimibe:

  • ciclosporin, a medicine used to treat psoriasis or after an organ transplant
  • medicines used to prevent blood clots, such as warfarin
  • other medicines used for lowering cholesterol (this does not include statins), such as colestyramine or bezafibrate


  • Thanks 1
Link to comment
Share on other sites

Have to play the long term health strategy, so I am always reading around about random stuff like this. 

Its kind of like a video game to see if you can beat your best scores on your blood work lol. HDL up 6 points, LDL down 15 points, GFR in range, BP 120/80 w/ RHR 65...bonus round lol.  As an example, not my actual scores. 

  • Like 1
Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


  • Create New...

Important Information