GameChanger Posted October 7, 2019 Share Posted October 7, 2019 Pain. 1983 Jun;16(2):129-43. Partial antagonism of placebo analgesia by naloxone. Grevert P, Albert LH, Goldstein A. Thirty subjects were given a placebo (intravenous saline), which was described as a known pain killer, once a week for 3 consecutive weeks. Experimental ischemic arm pain was produced prior to the placebo and again 1 h later. In a double blind procedure, half of the subjects received 10 mg of naloxone after placebo; the remaining subjects received naloxone vehicle. In addition to the placebo session, there were control and naloxone sessions each week to determine the normal changes in pain and the effect of naloxone on the pain, respectively, when no placebo was given. Significant placebo-induced analgesia was demonstrated, and a group of consistent placebo responders was identified. Although naloxone alone had no effect on the experimental pain, naloxone diminished the analgesic effectiveness of the placebo, suggesting that endogenous opioids are involved in producing placebo-induced analgesia. PMID: 6308540 1 Quote Link to comment Share on other sites More sharing options...
Dude_wheresmycarbs Posted November 13, 2019 Share Posted November 13, 2019 @GameChanger Many times studies about placebo has been provided and it has been proven to work. The question standing is what happens in the body and in the brain that triggers this effect of false belief? Can the body heal itself on its own? Because it seems very logical. You cant be given a candy (told that it is a pill for headache) and after 30 mins you start to feel a relief. Quote Link to comment Share on other sites More sharing options...
millenium girl Posted November 13, 2019 Share Posted November 13, 2019 I just took part in a study about Adenuric. It lasted 3 weeks and don't know if they gave me a placebo or the real stuff. I like that kinda studies, very interesting. Quote Link to comment Share on other sites More sharing options...
Dude_wheresmycarbs Posted November 14, 2019 Share Posted November 14, 2019 But be careful @millenium girl, some medications may have serious side effects. 1 Quote Link to comment Share on other sites More sharing options...
millenium girl Posted November 14, 2019 Share Posted November 14, 2019 47 minutes ago, Dude_wheresmycarbs said: But be careful @millenium girl, some medications may have serious side effects. I know but this one is supposed to improve heart function. Quote Link to comment Share on other sites More sharing options...
Dude_wheresmycarbs Posted November 16, 2019 Share Posted November 16, 2019 On 11/14/2019 at 6:47 PM, millenium girl said: I know but this one is supposed to improve heart function. I understand, but still its risky when its in test phase Quote Link to comment Share on other sites More sharing options...
millenium girl Posted November 19, 2019 Share Posted November 19, 2019 On 11/16/2019 at 7:14 PM, Dude_wheresmycarbs said: I understand, but still its risky when its in test phase It is not in a test phase. Adenuric is widely used worldwide. Quote Link to comment Share on other sites More sharing options...
Dude_wheresmycarbs Posted November 19, 2019 Share Posted November 19, 2019 1 hour ago, millenium girl said: It is not in a test phase. Adenuric is widely used worldwide. Hah sorry. I dont know why I was sure that I read that it is in test phase. Quote Link to comment Share on other sites More sharing options...
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