Id say start with 12.5mg and guage it from there. 25mg is at the top end. You'll definitely notice some bloat as this stuff packs on the water for most, including me, but its a different feel. I find i loose fat once my body becomes accustomed to it. I read this a long time ago and i believe it holds to be very true from all my research on this sarm. Also play with the schedule, i.e. morning or night before bed. I find it is best for me in the am i dont get as lethargic - this is another side.
After treatment with 10 mg MK-677, IGF-I concentrations increased 52 +/- 20% (65 +/- 6 to 99 +/- 9 micrograms/L, geometric mean +/- intrasubject SE, P < or = 0.05 vs. baseline), and 24 h mean GH concentrations increased 79 +/- 19% (0.14 +/- 0.01 to 0.26 +/- 0.02 microgram/L, P < or = 0.05 vs. baseline).
Following treatment with 50 mg MK-677, IGF-I concentrations increased 79 +/- 9% (84 +/- 3 to 150 +/- 6 micrograms/L, P < or = 0.05 vs. baseline) and 24-h mean GH concentrations increased 82 +/- 29% (0.21 +/- 0.02 to 0.39 +/- 0.04 microgram/L, P < or = 0.05 vs. baseline), respectively. Serum IGF binding protein-3 concentrations increased with both 10 mg (1.2 +/- 0.1 to 1.7 +/- 0.1 micrograms/L, P < or = 0.05) and 50 mg MK-677 (1.7 +/- 0.1 to 2.2 +/- 0.2 micrograms/L, P < or = 0.05).”
So in short at a lower dose GH concentrations were relatively the same, its the IGF-1 that was more elevated at the higher dose which some people are after. Yes it does help with healing also, i find my joints are more cushioned just after a few days. If you know you have legit MK this stuff works fast, increased hunger and vivid dreams. I gained 10 pounds in a week lol
No you can stack this with just about anything